Figure 2

Genome-wide array comparative genome hybridization result: 13q33.2→qter deletion. There are three icons from top to down in total (a-c). (a) A scatter plot of a copy number; a gray point shows the copy number calculated from a probe set and a red point represents the mean copy number calculated from consecutive 100 probe sets. The baseline in the middle indicates the normal copy number level. Upward deviation from the baseline indicates amplification and downward departure from the baseline represents deletion. (b) A schematic of copy number variant (CNV) segments identified based on the segmentation algorithm. The blue color represents deletion CNV. (c) A diagram of the loss of heterozygosity (LOH).