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Table 2 Immunohistochemical findings in spindle cell oncocytoma and the main differential diagnosesa

From: Spindle cell oncocytoma of the adenohypophysis in a woman: a case report and review of the literature

Diagnoses

Immunohistochemical markers

Spindle cell oncocytoma

S-100 protein, vimentin and EMA are expressed

Oncocytic variant of meningioma

EMA is expressed, vimentin is expressed and S-100 protein is negative

Granular cell tumour

CD68 is expressed

Pituicytoma

GFAP is expressed

Oncocytic neoplasm originating from salivary gland remnants

Epithelial markers are expressed, S-100 protein and EMA are negative

Oncocytic variant of a pituitary adenoma

Synaptophysin and chromogranin are expressed

  1. aEMA, epithelial membrane antigen; GFAP, glial fibrillary acidic protein.