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Table 2 Comparison of laboratory studies performed during patient's first and second admissions

From: Subacute herpes simplex virus type 1 encephalitis as an initial presentation of chronic lymphocytic leukemia and multiple sclerosis: a case report

Laboratory studies

First admission (2 to 9 February)

Second admission (11 to 21 March)

Normal range or value

Complete blood count

   

WBC (× 109/L)

11.82

9.12

4.8 to 10.8

Absolute lymphocytes (× 103/μL)

7.29

5.84

1.20 to 3.40

CSF lumbar puncture

   

RBC (cells/μL)

63

6

 

WBC (cells/μL)

6

8

0 to 5

Neutrophils (%)

0

3

 

Lymphocytes (%)

83

86

 

Monocytes (%)

17

10

 

Number of cells counted

18

Not measured

 

Glucose (mg/dL)

54

55

 

Total protein (mg/dL)

49

40

15 to 45

CSF rapid PCR for HSV-1

Positive

Negative

 

CSF cytology

Negative

Negative

 

CSF flow cytometry

Negative

Negative

 

Oligoclonal banding

   

CSF bands

Not measured

10

<4

Serum bands

 

0

 

CSF IgG index

   

CSF IgG index

 

0.9

<0.85

CSF IgG (mg/dL)

 

6.11

<8.1

CSF albumin (mg/dL)

 

32.3

<27.0

CSF IgG/albumin

Not measured

0.19

<0.21

CSF synthesis rate (mg/24 hours)

 

14.24

<12

Serum IgG (mg/dL)

 

849

600 to 1500

Serum albumin (mg/dL)

 

4010

3200 to 4800

Serum IgG/albumin

 

0.2

<0.4

CSF myelin basic protein (ng/mL)

Not measured

5.7

<1.5

  1. This table demonstrates the available studies performed during each of the patient's admissions that pertain to her diagnoses of chronic lymphocytic leukemia (complete blood count, CSF cytology, CSF flow cytometry), Herpes simplex virus type-1 encephalitis (CSF lumbar puncture, CSF rapid PCR for HSV-1), and multiple sclerosis (oligoclonal banding, CSF IgG index, CSF myelin basic protein).
  2. CSF = cerebrospinal fluid; HSV = herpes simplex virus; PCR = polymerase chain reaction; RBC = red blood cells; WBC = white blood cells.