Figure 3From: Complications of nephrogenic systemic fibrosis following repeated exposure to gadolinium in a man with hypothyroidism: a case report (A) Lower dermis and subcutaneous fat with widened and thickened fibrous septae and increased dermal fibroblastic proliferation with thickened collagen; (B) increased dermal fibroblastic proliferation with thickened collagen fibers; (C, D) immunohistochemistry stains of dermal fibroblastic cells are positive for factor 13a (C) and CD34 (D).Back to article page