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Table 1 Treatment modalities, corresponding laboratory values (TSH and Tg level) and MI results (FDG-PET and I-131 SPECT) for different time points during follow-up

From: Molecular imaging of potential bone metastasis from differentiated thyroid cancer: a case report

Parameter

Date (MM/YY format) and treatment

 

08/06

10/06

11/06

05/07

11/07

06/08

11/08

10/09

05/10

Treatment

Cementoplasty and posterior arthrodesis

Total thyroidectomy

First RIT (GBq level unknown)

Second RIT (GBq level unknown)

Third RIT (5.4 GBq)

Fourth RIT (5.5 GBq)

Fifth RIT (5.8 GBq)

Wait and see

Wait and see

TSH (mIU/L)

NA

NA

NA

NA

103

119

130

NA

< 0.02

Thyroglobulin (μg/L)

NA

NA

2357

805

891

1035

939

NA

606

I-131 SPECT

NA

NA

Positive uptake: thyroid bed, multiple foci in the lungs, osseous lesions T11, L3, os ilium, left femur

No uptake in the thyroid bed, decreasing uptake in the lungs, stable uptake in the osseous lesions

No uptake in the thyroid bed, os ilium, left femur decreasing uptake in the lungs, stable uptake in the spine lesions T11/L3

No uptake in the thyroid bed, os ilium, left femur decreasing uptake in the lungs, stable uptake in the spine lesions T11/L3

No uptake in the thyroid bed, os ilium, left femur decreasing uptake in the lungs, stable uptake in the spine lesions T11/L3

NA

NA

FDG-PET

NA

NA

NA

NA

NA

NA

Slight uptake in Pulmonary metastases, no uptake in spinal lesions T11/L3

Slight uptake in Pulmonary metastases, no uptake in spinal lesions T11/L3

NA

  1. FDG = fludeoxyglucose; NA = not available; PET = positron emission tomography; RIT = radioiodine treatment; Tg = thyroglobulin; TSH = thryotropin; SPECT = single photon emission computer tomography.