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Table 1 Patients with HIV-1 and Lyme neuroborreliosis co-infection; baseline data, clinical and laboratory characteristics

From: Lyme neuroborreliosis in HIV-1 positive men successfully treated with oral doxycycline: a case series and literature review

Patient no. Sex Age Years since HIV diagnosis CD4 cell count (cells/μL) Viral load at diagnosis of LNB (copies/mL) Symptoms of LNB CSF laboratory data Borrelia diagnosis History of tick bite
     nadir at diagnosis of LNB plasma CSF   Mono-nuclear cells (cells/μL) Albumin (mg/L)   
1 m 60 24 190 190 65,907 1,100,000 radicular pain, cognitive impairment 193 2790 CSF Bb-antibodies + positive Bb antibody index yes
2 m 39 6 280 390 83,400 448,000 hearing-loss, vertigo (pontine infarction) 492 2860 CSF Bb-antibodies + positive Bb antibody index no
3 m 62 6 180 320 < 20 219 dysgeusia, vertigo, incontinence, headache (normal pressure hydrocephalus) 93 2000 CSF Bb-antibodies + positive Bb antibody index no
4 m 50 5 180 450 nd nd headache, facial palsy 50 481 CSF Bb IgG seroconversion no
  1. CSF: cerebrospinal fluid; m: male; nd: no data; Bb: Borrelia burgdorferi. Reference values: CD4 cells > 500 cells/μL, CSF mononuclear cells < 5 cells/μL, CSF albumin < 420 mg/L.