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Table 1 Patients with HIV-1 and Lyme neuroborreliosis co-infection; baseline data, clinical and laboratory characteristics

From: Lyme neuroborreliosis in HIV-1 positive men successfully treated with oral doxycycline: a case series and literature review

Patient no.

Sex

Age

Years since HIV diagnosis

CD4 cell count (cells/μL)

Viral load at diagnosis of LNB (copies/mL)

Symptoms of LNB

CSF laboratory

data

Borrelia diagnosis

History of tick bite

    

nadir

at diagnosis of LNB

plasma

CSF

 

Mono-nuclear cells (cells/μL)

Albumin (mg/L)

  

1

m

60

24

190

190

65,907

1,100,000

radicular pain, cognitive impairment

193

2790

CSF Bb-antibodies + positive Bb antibody index

yes

2

m

39

6

280

390

83,400

448,000

hearing-loss, vertigo (pontine infarction)

492

2860

CSF Bb-antibodies + positive Bb antibody index

no

3

m

62

6

180

320

< 20

219

dysgeusia, vertigo, incontinence, headache (normal pressure hydrocephalus)

93

2000

CSF Bb-antibodies + positive Bb antibody index

no

4

m

50

5

180

450

nd

nd

headache, facial palsy

50

481

CSF Bb IgG seroconversion

no

  1. CSF: cerebrospinal fluid; m: male; nd: no data; Bb: Borrelia burgdorferi. Reference values: CD4 cells > 500 cells/μL, CSF mononuclear cells < 5 cells/μL, CSF albumin < 420 mg/L.