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Table 1 Reported sensitivity and specificity of commonly utilized dynamic biochemical diagnostic tests for determining the site of excess ACTH secretion

From: Failure of functional imaging with gallium-68-DOTA-D-Phe1-Tyr3-octreotide positron emission tomography to localize the site of ectopic adrenocorticotropic hormone secretion: a case report

Diagnostic Test

Sensitivity

Specificity

Overnight high dose dexamethasone suppression test (8 mg) [3]

59-92%

67-100%

IV dexamethasone suppression test [5]

95-100%

40-90%

Ovine CRH stimulation test [5]

85-93%

85-90%

IPS sampling (central: peripheral gradient) [6]

81-85%

90-100%