Rare association between cystic fibrosis, Chiari I malformation, and hydrocephalus in a baby: a case report and review of the literature

Table 1 Previous reports of cystic fibrosis (CF) and Chiari malformation

Reference	Age	Sex	Presenting signs and symptoms	Radiologic findings (extent of Chiari, ± aqueductal stenosis, ± hydrocephalus)	Treatment	Follow-up	Outcome
[10]	10 months	M	Swallowing dysfunction	Not reported	Chiari decompression	Not reported	Resolution of symptoms
[10]	18 years	M	Syncope	Not reported	Chiari decompression	Not reported	Resolution of symptoms
[10]	17 years	F	Numbness of extremities	Not reported	Chiari decompression	Not reported	Resolution of symptoms
[10]	three years	M	Recurrent vomiting	Not reported	None	Not reported	Symptoms unresolved
[10]	17 years	M	Persistent headache	Not reported	Chiari decompression	Not reported	Resolution of symptoms
[13]	four months	M	Failure to thrive	Aqueductal stenosis; hydrocephalus	VP shunt	three months	Death from sepsis
[13]	eight months	F	Failure to thrive, nystagmus	Tonsillar herniation with hydrocephalus	Chiari decompression and VP shunt	one year	Shunt malfunction and cerebral herniation
[15]	eight years	F	Thoracic scoliosis; gait instability; hand wasting	Chiari I with thoracic scoliosis and cervicothoracic syrinx	Chiari decompression	two months	Resolution of symptoms
Present report	10 months	M	Vomiting	2.2 cm of herniation; aqueductal stenosis; hydrocephalus	VP shunt	one month	Resolution of symptoms

ISSN: 1752-1947