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Table 1 Compiled from the literature review recently presented by Feletti et al [7] and a few other reports

From: Extensive central nervous system involvement in Merkel cell carcinoma: a case report and review of the literature

Total number of patients reported

18, including our case report

Age, range

45-71 years

Gender: male/female

12/4 (two not defined)

Location of CNS metastases

 

Parietal lobe

3

Meningeal

3

Cerebellum

2

Frontal

1

Frontoparietal

1

Hypophysis and cavernous sinus

1

Brainstem

1

Not defined

6

Other metastasis

13 of 18

Lymph nodes

8

Lungs

2

Liver

1

Choroidal

1

Cutaneous

1

Time since the detection of the primary tumor

0-4 years (50% <1 year)

Treatment for brain metastasis

 

Radiotherapy + chemotherapy

5

Surgical removal + radiotherapy + chemotherapy

4

Radiotherapy only

2

Surgical removal only

1

Chemotherapy only

1

Gamma knife

1

Not defined

4

Survival after diagnosis

1 month to >3 years