Figure 3
From: A rare case of "switch on and off" multi-system Langerhans cell histiocytosis in an adult patient
(A) Tissue slide revealing an obvious distortion of lung architecture (hematoxylin and eosin stain; original magnification, ×20). (B) Higher magnification (original magnification, ×200) of the slide in Figure 3A showing the characteristic ovoid Langerhans cells and eosinophils (hematoxylin and eosin stain). (C) The Langerhans cells demonstrate strong immunoreactivity, both nuclear and cytoplasmic, for S-100 protein (original magnification, ×400). (D) CD1a stain is also positive in Langerhans cells (original magnification, ×400).