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Table 1 The demographic, clinical, laboratory, radiological and outcome data for the 21 cases reported in the literature and in our patienta

From: Severe community-acquired adenovirus pneumonia in an immunocompetent 44-year-old woman: a case report and review of the literature

Patient characteristics

Our case

Previously reported cases (n= 21)

Demographics

  

   Age, yr

44

40 [18 to 60]

   Sex

Female

Male 12 (57)

Presenting symptoms

  

   Preceding history, days

3

5 [1 to 28]

   Fever

Yes

19 (90)

   Cough

Yes

17 (81)

   Dyspnea

Yes

15 (70)

   Myalgia

Yes

11 (57)

   Sore throat

Yes

6 (29)

   Abdominal pain

Yes

3 (14)

   Diarrhea

Yes

2 (10)

Examination findings

  

   Fever (temperature > 38°C)

Yes

17 (81)

   Chest signs

No

19 (90)

   Hypoxia

No

16 (66)

   Pharyngitis

Yes

4 (19)

   Conjunctivitis

No

4 (19)

   Rash

Yes

1 (5)

Laboratory tests

  

   Total white cell count (4 to 11 × 109/L)

6.6

7.7 [3.9 to 28]

   Neutrophilia (> 7 × 109/L)

No

7 (33)

   Lymphopenia (< 1.0 × 109/L)

Yes

11 (52)

   Thrombocytopenia (< 150 × 109/L)

No

4 (19)

   Elevated transaminases

No

6 (29)

   Elevated CPK

Yes

6 (29)

CXR appearance

  

   Normal

No

2 (10)

   Lobar consolidation

No

5 (24)

   Bilateral interstitial infiltrates

Yes

12 (57)

Clinical course/outcome

  

   Required ET intubation

Yes

14 (67)

   Time to Intubation, days

3

1.5 [0.25 to 8]

   Treatment with cidofovir

No

2 (10)

   Length of hospital stay, days

9

21 [3 to 123]

   Died

No

5 (24)

Adenovirus serotype

  

   3

No

4 (19)

   4

Yes

2 (10)

   7

No

5 (24)

   21

No

3 (14)

   Unknown

No

7 (33)

  1. aCPK, creatinine phosphokinase; CXR, Chest X ray; ET, endotracheal tube.
  2. Data are expressed as n (%) or median [range].