Human immunodeficiency virus infection and autoimmune hepatitis during highly active anti-retroviral treatment: a case report and review of the literature

Table 1 Characteristics of 11 reported patients with concomitant HIV and AIH^a

Case reports	Patient age (years)/gender	Onset	CD4^b/CD4^c	VL^b/VL^c	AIH score	Outcome	Other AI diseases	ART
German et al. [2]	38^d/man	Chronic	216/384	81,000/< 50	Probable	Excellent	Vetilligo	Yes
Coriat and Podevin [7]	48/woman	Acute	250	Undetectable	Probable	Died	None	Yes
Puius et al. [3]	29/man	Chronic	259/174	7122/27,732	Probable	Excellent	None	Yes
	45^d/woman	Chronic	253/297	8687/< 50	Probable	Excellent	DILS	Yes
	65/woman	Acute	200/922	Undetectable/< 75	Definite	Excellent	None	Yes
O'Leary et al. [4]	44^d/woman	Chronic	269/526	4927/< 50	Definite	Excellent	Grave's disease	Yes
Wan et al. [5]	56/man	Chronic	331/NA	232,734/NA	Probable	Died	None
	54/man	Chronic	357/213	5104/NA	Probable	Probable	Cirrhosis	Yes
	55/woman	Chronic	174/NA	< 50/NA	Probable	Probable	Poor	Yes
	49/woman	Acute	286/NA	69,318/NA	Definite	Definite	Died	Yes
Our patient	42^d/woman	Acute	157/232	120,000/< 50	Definite	Excellent	SLE	Yes

^aTwo patients are not included because of lack of complete clinical data. HIV = human immunodeficiency virus; AIH = autoimmune hepatitis; AI, autoimmune; ART = antiretroviral treatment; VL = viral load; DILS = diffuse infiltrative lymphocytic syndrome; SLE = systemic lupus erythematosus; ^bprior to initiating highly active antiretroviral treatment (HAART); ^cafter initiating HAART; ^dpatients with significant viral suppression on HAART who developed AIH.

ISSN: 1752-1947