Figure 1

Photomicrographs of the renal biopsy. (a) Lupus nephritis class IV-G(A) + V (hematoxylin and eosin stain; original magnification, × 200). (b) Glomerulus showing global endocapillary proliferation, fibrinoid necrosis, neutrophilic infiltration and capillary wall thickening (hematoxylin and eosin stain; original magnification, × 600). (c) Glomerulus showing mesangial expansion with hypercellularity and occlusion of peripheral lumina (periodic acid-Schiff stain; original magnification, × 600). (d) Glomerulus showing thickened basement membranes with numerous spikes and occasional dual contour (methenamine silver stain; original magnification, × 600). (e) Glomerulus showing areas of bright red fibrinoid necrosis (trichrome stain; original magnification, × 600). (f) Minimal tubulointerstitial fibrosis (trichrome stain; original magnification, × 100).