Table 1 Drugs administered during our patient's stay at the intensive care unit.
From: Highly variable pharmacokinetics of dexmedetomidine during intensive care: a case report
Start (day) | Stop (day) | Dosage | |
|---|---|---|---|
Regularly administered drugs | |||
Calcium glubionate | 3 | 21 | 90 mg × 2 - 6 iv |
Enoxaparin | 3 | 9 | 20 mg to 40 mg when needed for CVVHDF |
10 | 54 | 40 mg × 1 sc | |
Sodium polystyrene sulfonate | 3 | 3 | 30 g × 1 pr |
Pantoprazol | 3 | 54 | 40 mg × 1 iv |
Imipenem | 3 | 39 | 250 mg to 1000 mg × 3 iv |
Ondansetron | 3 | 3 | 4 mg × 2 iv |
Lactulose | 6 | 9 | 20 g × 3 po |
Vancomycin | 8 | 54 | 1000 mg × 2 iv (based on the serum concentration) |
Metronidazole | 11 | 19 | 400 mg × 3 po |
19 | 26 | 500 mg × 3 iv | |
Fluconazole | 12 | 51 | 400 mg × 1 iv |
Hydrocortisone | 13 | 15 | 100 mg × 3 iv |
Ciprofloxacin | 18 | 39 | 400 mg × 2 iv |
Tigecycline | 39 | 54 | 50 mg × 2 iv |
Infusions | |||
Short-acting insulin | 3 | 54 | 0.5 - 20 IU/h |
Furosemide | 3 | 3 | 1000 mg/day |
6 | 36 | 70 - 1000 mg/day | |
Norepinephrine | 3 | 31 | Maximum dose 0.19 μg/kg/min |
Propofol | 3 | 36 | See Figure 1. |
Dexmedetomidine | 17 | 41 | See Figure 1. |
Metoprolol | 38 | 40 | 1 - 2 mg/h |
Clonidine | 40 | 51 | Maximum dose 2.2 μg/kg/h |
Drugs administered when needed | |||
Propofol | 3 | 37 | 20 - 50 mg iv |
Diazepam | 3 | 3 | 2.5 mg iv |
Lorazepam | 26 | 41 | 1 - 4 mg iv |
Haloperidol | 36 | 55 | 2.5 - 5 mg iv |
Fentanyl | 3 | 31 | Occasional doses of 50 - 200 μg iv |
Oxycodone | 3 | 53 | 5 - 10 mg iv |
Acetaminophen | 11 | 21 | Occasional doses of 1000 mg po/iv |
Furosemide | 3 | 52 | 5 - 10 mg iv |
Ephedrin | 3 | 3 | 5 mg iv |
Rocuronium | 3 | 32 | Occasional doses of 10 - 50 mg iv |
Indapamide | 15 | 15 | 2.5 mg × 1 |
Metoprolol | 26 | 42 | Occasional doses of 2.5 - 5 mg iv |