Figure 2

(a, b, c, d). Pathological findings of the resected specimen showed numerous cystically dilated ducts surrounded by numerous proliferating smooth-muscle bundles without islets or acini from the submucosal layer to the proper muscular layer (a, b). Well differentiated adenocarcinoma cells proliferating diffusely in an area ranging from the submucosal layer to the subserosa was observed in a direct transition to dysplastic ductal structures (a, c, d). (hematoxylin-eosin, a: × 20, b: × 100, c: × 100, d: × 200)