| |
Presentation
|
After 1st adverse event
|
After 2nd adverse event
|
Normal range
|
|---|
|
AST (U/L)
|
112
|
115
|
137
|
5-41
|
|
ALT (U/L)
|
71
|
81
|
84
|
7-41
|
|
Bilirubin (mg/dL)
|
1.7
|
2.8
|
2.7
|
<1
|
|
Creatinine (mg/dL)
|
0.8
|
0.9
|
0.8
|
0.7-1.3
|
|
Urea (mg/dL)
|
46
|
55
|
50
|
10-50
|
|
Albumin (g/dL)
|
1.5
|
1.6
|
1.6
|
3.6-4.8
|
|
Haemoglobin (g/dL)
|
9.4
|
11
|
10
|
13-17
|
|
WBC (103/μL)
|
3.9
|
4.9
|
5.0
|
4.0-10.0
|
|
Platelets (103/μL)
|
61
|
73
|
78
|
150.0-450.0
|
|
CRP (mg/L)
|
15
|
11
|
12
|
<5
|
|
PT (INR)
|
1.2
|
1.2
|
1.2
|
0.8-1.2
|
|
Na+ (mEq/L)
|
139
|
139
|
140
|
135-145
|
|
K+ (mEq/L)
|
4.7
|
5.0
|
4.2
|
3.6-5.2
|
|
pH
|
7.43
|
7.43
|
7.50
|
7.35-7.45
|
|
HCO3 (mmol/L)
|
23.6
|
22.1
|
24.6
|
21-23
|
- AST: aspartate aminotransferase; ALT: alanine aminotransferase; WBC: white blood cell; PT: prothrombin time; INR: international normalized ratio; Na+: sodium, K+: potassium, HCO3: bicarbonate.
