Severe hepatic encephalopathy in a patient with liver cirrhosis after administration of angiotensin-converting enzyme inhibitor/angiotensin II receptor blocker combination therapy: a case report

Table 1 Blood exams and gas analysis upon admission and during the two episodes of encephalopathy

	Presentation	After 1st adverse event	After 2nd adverse event	Normal range
AST (U/L)	112	115	137	5-41
ALT (U/L)	71	81	84	7-41
Bilirubin (mg/dL)	1.7	2.8	2.7	<1
Creatinine (mg/dL)	0.8	0.9	0.8	0.7-1.3
Urea (mg/dL)	46	55	50	10-50
Albumin (g/dL)	1.5	1.6	1.6	3.6-4.8
Haemoglobin (g/dL)	9.4	11	10	13-17
WBC (10³/μL)	3.9	4.9	5.0	4.0-10.0
Platelets (10³/μL)	61	73	78	150.0-450.0
CRP (mg/L)	15	11	12	<5
PT (INR)	1.2	1.2	1.2	0.8-1.2
Na⁺ (mEq/L)	139	139	140	135-145
K⁺ (mEq/L)	4.7	5.0	4.2	3.6-5.2
pH	7.43	7.43	7.50	7.35-7.45
HCO₃ (mmol/L)	23.6	22.1	24.6	21-23

AST: aspartate aminotransferase; ALT: alanine aminotransferase; WBC: white blood cell; PT: prothrombin time; INR: international normalized ratio; Na⁺: sodium, K⁺: potassium, HCO₃: bicarbonate.