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Table 1 Clinicopathological features in case reports of extracapsular parathyroid hemorrhages

From: Neck emergency due to parathyroid adenoma bleeding: a case report

Author (year)

#

Clinical features

Ca2+ (normal values)

T

Histology (Ø = cm)

Capps R (1934) [2]

1

Weakness, sore throat, cervical swelling/ecchymosis, dysphagia, dyspnea

NA

5 weeks

Adenoma (Ø = 7)

Berry BE (1974) [3]

1

Weakness, retrosternal pain, signs of superior vena caval compression

NA

1 day

Adenoma (Ø = 5)

Santos GH (1975) [4]

1

Retrosternal pain, dizziness, hypotension, hypercalcemia

NA

1 day

Adenoma (Ø = 8)

Jordan FT (1981) [5]

1

Anterior cervical pain, swelling and ecchymosis, dysphagia

13.3 mg/dL

1 month

Hyperplasia (Ø = 6)

Roma J (1985) [6]

1

Hoarseness, dysphagia, cervical swelling, cervical-thoracic ecchymosis

3.00 mmol/L

1 day

Hyperplasia

Simcic KJ (1989) [7]

1

Painful cervical swelling, dysphagia, dyspnea

4 mmol/L (2.14-2.52)

2 weeks

Adenoma (Ø = 4.5)

Massard JL (1989) [8]

1

Difficulty swallowing, dysphonia, cervical pain, cervical ecchymosis

3.15 mmol/L

10 hours

Adenoma

Hotes LS (1989) [9]

1

Hoarseness, dysphagia, discomfort in the anterior area, ecchymosis

Normal

3 days

Adenoma

Alame A (1990) [10]

1

Difficulty swallowing, dysphonia, cervical-thoracic ecchymosis

2.86 mmol/L

1 day

Adenoma

Mantion G (1990) [11]

1

Dysphagia, dyspnea, ecchymosis

2.67 mmol/L

2 days

Adenoma (Ø = 2.5)

Amano Y (1993) [12]

1

Hoarseness, dysphagia, cervical swelling and ecchymosis

Normal

2 days

Adenoma (Ø = 5.6)

Korkis AM (1993) [13]

1

Hoarseness, dysphagia, cervical swelling and cervical-thoracic ecchymosis

11.6 mg/dL

1 day

Adenoma (Ø = 4)

Jougon J (1994) [14]

1

Dysphagia, cervical swelling and cervical-thoracic ecchymosis

2.9 mmol/L

1 day

Adenoma (Ø = 3)

Menegaux F (1997) [15]

1

Cervical pain, dysphagia, dyspnea

2.62 mmol/L

1 day

Adenoma

Hellier WPL (1997) [16]

1

Dysphagia, dysphasia, cervical-thoracic ecchymosis

Elevated

1 day

Adenoma

Ku P (1997) [17]

1

Hoarseness, cervical pain and ecchymosis

3.15 mg/dL

1 day

Adenoma (Ø = 2)

Kihara M (2001) [18]

1

Painful cervical swelling and cervical-thoracic ecchymosis

Normal

1 month

Adenoma (Ø = 2)

Kozlow (2001) [19]

1

Dysphagia, odynophagia, cervical swelling

11.3 mg/dL (8.4-10.2)

7 days

Adenoma

Nakajima J (2002) [20]

1

Retrosternal pain, cervical-thoracic ecchymosis

Normal

3 weeks

Adenoma (Ø = 3.5)

Govindaraj S (2003) [21]

1

Hyper-normo-calcemia, right-sided headaches, severe throat pain

13 mg/dL

2 weeks

Adenoma

Taniguchi I (2003) [22]

1

Cervical swelling, pain, dysphagia, cervical-thoracic ecchymosis

NA

1 month

Cyst (Ø = 6)

Maweja S (2003) [23]

2

Painful cervical swelling and cervical-thoracic ecchymosis

2.57; 2.80 mmol/L

2 days

Adenoma

Tonerini M (2004) [24]

1

Painful cervical swelling

NA

1 day

Adenoma

Akimoto T (2005) [25]

1

Left pleural effusion in IPT II at chest X-ray and computed tomography scan

Elevated

1 day

Hyperplasia

Devezè A (2006) [1]

2

1. Dysphagia cervical hematoma, hypercalcemia

2.57 mmol/L

1 week

1. Adenoma

  

2. Latero-cervical pain and ecchymosis

 

5 days

2. Adenoma

Merant-Boschin I (2009)

1

Painful cervical swelling, dysphonia, dyspnea

3.18 mmol/L (2.10-2.55)

2 days

Adenoma (Ø = 4.0)

  1. Notes: #, number of cases described; [Ca2+]: calcium level; T: time of onset; Normal: in the normal range; NA: Not assessed.