Unexpected depletion in plasma choline and phosphatidylcholine concentrations in a pregnant woman with bipolar affective disorder being treated with lithuim, haloperidol and benztropine: a case report

Table 3 Plasma phosphatidylcholine and choline concentration.

		Bipolar patient	Means ± S.D. N = 3
PHOSPHATIDYLCHOLINE (nmoles/ml)
	10–13 weeks	2158.96	1573.24 ± 50.73
	19–23 weeks	2180.34	1769.70 ± 324.59
	34–37 weeks	1677.86	1716.11 ± 423.70
FREE CHOLINE(nmoles/ml)
	10–13 weeks	11.17	8.94 ± 1.81
	19–23 weeks	7.62	8.77 ± 1.48
	34–37 weeks	6.89	10.99 ± 1.94

The table shows the plasma concentrations of phospahtidylcholine and choline for trimester 1 (10–13 weeks gestation), trimester 2 (19–23 weeks gestation) and trimester 3 (34–37 weeks gestation) for bipolar and control patients. The patient with bipolar affective disorder showed depletion of both compounds rather than the expected increase.

ISSN: 1752-1947