Figure 1

Renal biopsies. (A) High power haematoxylin and eosin stained section of the first biopsy showing hard, fractured casts with associated giant cell reaction. There is a peritubular inflammatory cell infiltrate, with significant interstitial fibrosis and tubular atrophy. (B) High power haematoxylin and eosin stained section of the second biopsy demonstrating resolution of myeloma casts. There is partial resolution of the interstitial inflammatory infiltrate. The degree of interstitial fibrosis and tubular atrophy remained unchanged.