Figure 2

Cytogenetic analysis of bone marrow cells performed on the day of admission to our hospital demonstrating monosomy 7 and an accessorial translocation t (3;8). A) This image displays detection of monosomy 7 by fluorescence in-situ hybridization using a CEP 7 probe (Vysis, USA). Monosomy 7 was found in 78.5% of the examined metaphases. B) This image shows classical cytogenetic banding of a representative metaphase of the patient with glycogen storage disease type Ib. In total, 34 metaphases have been analyzed demonstrating a monosomy 7 in 33 metaphases and a translocation t (3;8)(q26;q24).