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Table 2 Reported cases of metformin-induced hemolytic anemia

From: Fatal hemolytic anemia associated with metformin: A case report

Case report

Patient's age (years)

Gender

Time from starting metformin to onset of symptoms

Direct Coombs

G6PD level

Recurrence of hemolysis with metformin rechallenge

Outcome

Lin et al. [1]

46

Male

10 days

'Equivocal'

Normal

Yes

Recovery

Kashyap and Kashyap [2]

51

Female

9 days

Positive (-IgG, +C3)

Normal

Yes

Recovery

Meir et al. [3]

68

Female

14 days

Negative

Decreased

N/A

Recovery

Packer et al. (this study)

56

Male

1 to 2 days

Positive (+IgG, -C3)

N/A

N/A

Death