From: Primary glioblastoma in the pineal region: a case report and review of the literature
Author/Year | Age/Sex | Symptoms | Radiological findings | Leptomeningeal dissemination | Treatment | Survival |
---|---|---|---|---|---|---|
Bradfield et al./1972 | 53/F | N-A | Obstructive HDC, mass in post. 3rd ventricle | No on autopsy | Resection | Postoperative death |
Bradfield et al./1972 | 5/F | N-A | Obstructive HDC, mass in post. 3rd ventricle | No on autopsy | Shunt | 27 mos |
DeGirolami et al./1973 | 3 cases | Intracranial hypertension, vertical gaze palsy in one case | N-A | N-A | RT for all cases, Resection for only one case | N-A |
Kalyanaraman/1979 | 68/F | Ataxia, confusion, urinary incontinence, upgaze limitation | CT: HDC, calcified midline mass | N-A | Resection, RT | 4 mos |
Norbut et al./1981 | 36/M | HA, blurry vision, Parinaud's syndrome | CT: HDC, mass in post. 3rd ventricle | Yes on autopsy (4th ventricle, leptomeninges of cerebral cortex, interpeduncular fossa, brain stem, and spinal cord) | Shunt, RT | 4 mos |
Frank et al./1985 | 52/F | Intracranial hypertension, oculomotor disturbances | HDC, mass in 3rd ventricle | N-A | Stereotactic biopsy, RT | 4 mos |
Edwards et al./1988 | 12/F | N-A | N-A | N-A | Resection, RT, Chemotherapy | 18 mos |
Vaquero et al./1990 | 63/M | HA, changing of behavior | CT: rounded hyperdense mass with ring enhancement | N-A | Shunt, Resection, Whole brain RT | 6 mos |
Pople et al./1993 | 6/F | HA, N/V, diplopia, decreased visual acuity, 6th cranial nerve palsy, upgaze limitation | CT & MR: HDC, enhancing mass | Yes on FU CT (frontal & occipital lobes, scattered leptomenges) | Shunt, Resection, local RT, Chemotherapy | 4 mos |
Cho et al./1998 | 10–15/F | N-A | N-A | N-A | Resection, RT | 6 mos |
Gasparetto et al./2003 | 29/F | HA, drowsiness, fever, dizziness, seizure, | CT & MR: ill-defined heterogeneously enhanced mass with extension to thalamus | No | Shunt, Resection | 2 mos |
Toyooka et al./2005 | 49/M | HA, diplopia, memory disturbance | MR: irregular heterogeneously enhanced mass | Yes on FU MR (lateral ventricle, pons, pontomedullary junction) | Shunt, Resection, Chemotheraphy (ACNU), local RT | 11 mos |
Amini et al./2006 | 40/M | HA, N/V, diplopia, blurry vision | CT: Obstructive HDC, strong enhancement, punctuate calcification MR: heterogenously enhancing with central necrosis, extension into midbrain | Yes on initial MR (cbll, medulla, temporal lobe) | Endoscopic TVB, Resection, Shunt, Whole brain RT, Chemotherapy (Temodar) | 5 mos |
Amini et al./2006 | 43/M | HA, disequilibrium, decreased level of mental status | MR: heterogenously enhancing, HDC | Yes on FU MR (intraventricular) | TVB, Resection, Whole brain RT, Chemotherapy | 7 mos |
Amini et al./2006 | 52/F | HA, N/V, diplopia, blurry vision, upgaze palsy | MR: heterogenously enhancing with central necrosis, obstructive HDC | Yes on FU MR (lateral ventricle, leptomeninges of brain & spine) | Endoscopic TVB, RT | 2 mos |
Present case/2006 | 68/M | HA, N/V, Ataxia | CT: HDC, hypodense mass MR: irregular heterogeneously ring-enhanced mass with central necrosis | Yes on initial MR (4th ventricle) | Resection, Shunt | 2 mos |