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Table 1 Summary of patient's clinical findings relative to acromegaly and the three hereditary cancer susceptibility syndromes considered

From: A possible new syndrome with growth-hormone secreting pituitary adenoma, colonic polyposis, lipomatosis, lentigines and renal carcinoma in association with familial testicular germ cell malignancy: A case report

Patient's Findings

Acromegaly

Hereditary Syndrome

  

Cowden syndrome

Carney complex

MEN1

Seminoma

X

 

XX*

 

Pituitary adenoma (GH-producing)

XX

 

XX

XX

Colon adenomatous polyps

XX

   

Colon harmatomatous polyps

 

XX

  

Colon hyperplastic polyps

    

Renal cell carcinoma

X

X

  

Lipomas

 

XX

 

XX

Lentigines

  

XX

 
  1. XX: Classical syndrome-related findings
  2. X: Findings are less clearly established as part of the syndrome
  3. * Testicular cancers associated with Carney complex are typically large-cell calcifying Sertoli cell tumors or Leydig cells tumors of the testis