An epidermal growth factor receptor compound mutation of L858R with S768I in advanced non-small-cell lung cancer: a case report

Table 1 Clinical case summaries—insights from the literature

Case no.	Age, years	Sex	Mutation type	Treatment	Response
Our case	64	Male	L858R + S768I	Afatinib	GR
Svaton et al. [31]	63	Female	G719X + S768I	Gefitinib	GR
Masahiro et al. [32]	72	Female	G719X + S768I	Afatinib	GR
Yan et al. [33]	62	Female	del 2239_2248 + insC + L858R	Erlotinib	PD
Toshiki et al. [34]	72	Male	G719X + S768I	Osimertinib	GR
Simionato et al. [35]	69	Female	G719A + V769M	Osimertinib	GR
Juan et al. [36]	43	Female	19-Del + T790M	Chemotherapy	PD
He et al. [37]	64	Female	G724S + R776H	Afatinib	GR
Bao et al. [38]	36	Male	R670W + H835L + L833V	Afatinib + osimertinib	GR
Yang et al. [39]	N/A	Male	H773L + V774M	Osimertinib	GR
Li et al. [40]	53	Female	L833V + H835L	Aumolertinib	GR

ISSN: 1752-1947