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Fig. 2 | Journal of Medical Case Reports

Fig. 2

From: Abnormal white matter tracts resembling pencil fibers involving prefrontal cortex (Brodmann area 47) in autism: a case report

Fig. 2

Immunostaining with cell-specific markers in tissue sections that were adjacent to the section shown in Panel 1c. The images were taken within the pencil fibers indicated by the insets in Panels 1a and 1c, and shown in Nissl staining at higher power in Panel 1d. a–f Markers for glial cells show the presence of glial cells within the cortical pencil fibers: Sox 10 and Olig2 for oligodendrocytes, S100 and GFAP for astrocytes, Iba 1 for microglial cells and CD68 for activated microglia. g, h Axonal neurofilament 312 and neurofilament H non-phosphorylated 132 demonstrate the presence of axonal fibers within the pencil fibers. Scale bar: 150 μm

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Journal of Medical Case Reports

ISSN: 1752-1947