Table 3 Summary of prior cases of Doege-Potter syndrome
Author | Year | Case information |
|---|---|---|
Doege [1] | 1930 | The patient presented with facial flushing and symptoms of irrationality described as ‘maniacal seizures’ noted to improve with treatment by rectal glucose, morphine and scopolamine. Symptoms continue to recur and urine analysis demonstrated traces of acetone. The patient was found to have 26×16cm tumor filling nearly the entire left thoracic cavity, and was treated with surgical excision and noted to be without recurrence at a three-year follow-up. |
Potter [2] | 1930 | The patient was found to be delirious at times and was found to have a large tumor filling the entire left side of the thoracic cavity. The patient subsequently underwent two-stage surgical resection five days apart and made an uneventful recovery. |
Arkless [18] | 1942 | The patient had a history of convulsive seizures and was found to have a left subphrenic mass. Removal resolved the seizures. Seven years later the patient presented with hypoglycemia. This was managed on a high carbohydrate diet and the patient died. A spindle cell sarcoma of the left chest was found postmortem. |
Hines [19] | 1943 | A patient with recurrent hypoglycemia was found to have a sarcoma of the right upper abdomen. |
Skillern et al.[20] | 1954 | The patient had two large tumors composed of round and spindled cells and was found to have recurrent hypoglycemia. |
Frantz and Porter [21] | 1956 | The patient presented with recurrent hypoglycemia and was found to have a large pelvic mass encasing the ovary, thought to be a spindle cell neoplasm. |
Holten [22] | 1957 | A patient with a spindle cell tumor causing hypoglycemia. |
Scholz et al. [23] | 1957 | Two cases of patients who presented with recurrent hypoglycemia. In one patient, surgical resection of the tumor (described as a renal fibrosarcoma) resolved the hypoglycemia. |
August and Hiatt [24] | 1958 | Patient with frequent episodes of hypoglycemia that ceased with surgical resection of a large intrathoracic fibrosarcoma. |
Grilliat et al.[25] | 1970 | Tumor described as a pleural mesothelioma associated with hypoglycemia. |
Ellorhaoui and Graf [26] | 1976 | Patient with an intrathoracic tumor found to have hypoglycemia and diagnosed with Doege-Potter syndrome. |
Vollmar and Wockel [27] | 1977 | Tumor of the mesenchyme in the renal pelvis with malignant spread to lymph nodes and pathologically classified as malignant histiocytoma. |
Payne and Davison [28] | 1979 | Intrathoracic spindle cell tumor. |
Kecskés et al. [29] | 1979 | Thoracic mesenchymal tumor treated with surgical resection. |
Dao et al. [30] | 1984 | Pleural tumor in a patient with hypoglycemia. |
Heinrich et al. [31] | 1984 | Tumor described as an intrathoracic fibroma. |
Lessel and Erbstosser [32] | 1984 | Malignant fibrous histocytoma of the right lung that infiltrated the spinal column causing paralysis, no metastatic disease identified. |
Roy et al.[33] | 1992 | Recurrent SFT of the pleura. |
Abonyi et al.[34] | 1992 | Left-sided pleural mesothelioma and electron microscopy demonstrated neurosecretory granules thought to be insulin-like growth factor II-like material. |
Gullo et al.[8] | 1999 | Abdominal hemangiopericytoma treated with resection, developed recurrence that was treated with chemotherapy and radiotherapy, with subcutaneous biosynthetic growth hormone and prednisone to mitigate symptoms. |
Chamberlain and Taggart [5] | 2000 | Tumor described as a sub-pleural fibroma measuring 23×21×12cm, treated with surgical resection and noted to have complete recovery. |
Herrmann et al. [35] | 2000 | Malignant fibrous histiocytoma of the lung with tumor size described as 13×8cm. |
Zafar et al. [36] | 2003 | Pleural SFT measuring 19×15×14cm. |
Kafih et al.[37] | 2005 | Pleural fibrous tumor involving entire left hemithorax. |
Balduyck et al. [38] | 2006 | Pleural SFT measuring 22×19×7cm. |
Lucas and Ledgerwood [39] | 2006 | Malignant SFT of small bowel mesentery, measuring 10×12×20cm. |
Hirai[40] | 2006 | Pleural SFT measuring 10.9×9.8×9.4cm treated with surgical resection, found to have corresponding resolution of hypoglycemia associated with decrease in serum insulin-like growth factor II level postoperatively. |
Milenković et al. [41] | 2007 | Benign SFT involving almost the entire hemithorax. |
Kalebi et al. [42] | 2009 | Pleural SFT measuring 20×15×10cm, treated with surgical resection. |
Lee et al. [43] | 2010 | Thoracic SFT described pathologically as a low malignant potential tumor. |
Fung and Crook [44] | 2011 | Patient with tumor associated with spontaneous hypoglycemia. |
Campos et al.[45] | 2012 | Pleural SFT measuring 27×25×11.5cm. |
Rosseel et al. [46] | 2012 | Patient with hypoglycemia and found to have a right thoracic mass. |
Herrak et al. [47] | 2012 | Doege-Potter syndrome diagnosed in patient with a pleural tumor. |