Figure 4

Temporal profile of cytokines in our patient's sera. The following 15 cytokines were measured in the sera taken after day 34: interleukin (IL)-2, IL-3, IL-4, IL-5, IL-6, IL-10, IL-13, IL-15, IL-17, eotaxin-1, eotaxin-3, granulocyte colony stimulating factor (G-CSF), granulocyte-macrophage colony stimulating factor (GM-CSF), tumor necrosis factor α (TNFα), and interferon γ (IFNγ). The dashed line in the each panel represents the upper limit of the 95% confidence interval (95% CI) estimated from the healthy controls. Day 36 (when prednisolone was started at 60 mg/day) and day 122 (when prednisolone was raised from 3 mg/day to 40 mg/day) are specifically labeled on the time axis. IL-3, IL-4, IL-17, and IFNγ, which were consistently within the 95% CI of controls, were thus omitted.