Table 2 Accordance of the presented patient with the Yamaguchi criteria for the diagnosis of adult-onset Still’s disease
From: Suppurative necrotizing granulomatous lymphadenitis in adult-onset Still’s disease: a case report
Yamaguchi criteria (require the presence of five features, with at least two being major diagnostic criteria): | Patient’s characteristics |
|---|---|
Major Yamaguchi criteria: | |
1. Fever of at least 39°C lasting at least one week. | + |
2. Arthralgias or arthritis lasting two weeks or longer. | – |
3. Typical rash (maculopapular, nonpruritic) during febrile episodes. | + |
4. Leukocytosis (10,000/μL or greater), with at least 80% granulocytes. | + |
Minor Yamaguchi criteria: | |
1. Sore throat | – |
2. Lymphadenopathy | + |
3. Hepatomegaly or splenomegaly | – |
4. Abnormal liver function studies | – |
5. Negative antinuclear antibodies and rheumatoid factor. | + |
Exclusions | |
1. Infection, especially sepsis and infectious mononucleosis | ✓ |
2. Malignancies, especially lymphomas | ✓ |
3. Rheumatic diseases known to mimic adult Still’s disease | ✓ |