Isolated angioedema of the bowel due to C1 esterase inhibitor deficiency: a case report and review of literature

  • Shivangi T Kothari1Email author,

    Affiliated with

    • Anish M Shah1,

      Affiliated with

      • Deviprasad Botu2,

        Affiliated with

        • Robert Spira1,

          Affiliated with

          • Robert Greenblatt3 and

            Affiliated with

            • Joseph Depasquale1

              Affiliated with

              Journal of Medical Case Reports20115:467

              DOI: 10.1186/1752-1947-5-467

              Received: 29 July 2011

              Accepted: 20 September 2011

              Published: 20 September 2011

              Correction

              Following the publication of our article [1] an error in the discussion section was noted. In the description of the five phases of abdominal pain attacks associated with classic hereditary angioedema [2], we incorrectly stated the phases and described phase V instead of phase zero.

              Phase I starts with a period of non-cramping abdominal discomfort followed by (phase II) a crescendo phase which leads to (phase III) severe pain. Phase III is associated with vomiting and occasional diarrhea. Hypovolemia and hemoconcentration can occur as a result of a combination of events including vasodilatation, fluid shifts with edema of the bowel, ascites, and volume depletion related to vomiting and diarrhea. Phase IV refers to a decrescendo phase, which is a self limiting phase for untreated abdominal pain. Phase V refers to the resolution of pain, which can occur as often as twice a week

              Should read

              Phase zero also known as Prephase which includes fatigue, irritability, sensitivity to noise, nausea, and erythema marginatum. Phase I starts with a period of non-cramping abdominal discomfort followed by (phase II) a crescendo phase which leads to (phase III) severe pain. Phase III is associated with vomiting and occasional diarrhea. Hypovolemia and hemoconcentration can occur as a result of a combination of events including vasodilatation, fluid shifts with edema of the bowel, ascites, and volume depletion related to vomiting and diarrhea. Phase IV refers to a decrescendo phase, which is a self limiting phase for untreated abdominal pain

              Authors’ Affiliations

              (1)
              Department of Gastroenterology, School of Health and Medical Sciences Seton Hall University
              (2)
              Department of Internal Medicine, Trinitas Hospital
              (3)
              Department of Gastroenterology, Trinitas Hospital

              References

              1. Kothari ST, Shah AM, Botu D, Spira R, Greenblatt R, Depasquale J: Isolated angioedema of the bowel due to C1 esterase inhibitor deficiency: a case report and review of literature. Journal of Medical Case Reports 2011, 5:62.PubMedView Article
              2. Bork K, Staubach P, Eckardt AJ, Hardt J: Symptoms, Course, and Complications of Abdominal Attacks in Hereditary Angioedema due to C1 Inhibitor Deficiency. Am J Gastroenterol 2006, 101:619–27.PubMedView Article

              Copyright

              © Kothari et al; licensee BioMed Central Ltd. 2011

              This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://​creativecommons.​org/​licenses/​by/​2.​0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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