Table 1 Demographic and clinical details of patients treated with adalimumab
Number | Case | Luminal + FCD | Fistula type | Previous failed and/or intolerant therapies | Current treatment | Adverse effects | Treatment outcome |
|---|---|---|---|---|---|---|---|
1 | 44, M ileo-colonic CD | Yes | Enterocutaneous, post-operative | Parenteral nutrition Antibiotics - ciprofloxacine and metronidazole | Adalimumab monotherapy [160-80-40] | no | Luminal disease remission Fistula healing |
3 | 20, F ileo-colonic CD peri-anal disease | Yes | Peri-anal | Corticosteroid resistant Antibiotics - ciprofloxacine and metronidazole Azathioprine (fever and pancreatitis) Methotrexate (hepatitis) Reaction to infliximab (laryngismus) | Corticosteroids (tapered off) plus Adalimumab [160-80-40] Seton drainage | no | Luminal disease remission Fistula healing |
2 | 18, F ileo-colonic CD | Yes | Enterocutaneous, post-operative | No | Adalimumab monotherapy [160-80-40] | no | Luminal disease remission Fistula healing |