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Moderate size infantile haemangioma of the neck – conservative or surgical treatment? : a case report

Journal of Medical Case Reports20082:52

DOI: 10.1186/1752-1947-2-52

Received: 05 October 2007

Accepted: 19 February 2008

Published: 19 February 2008

Abstract

Introduction

Infantile haemangioma is the commonest benign tumour in infancy. While the management of the majority of small haemangiomas consists of simply watching or steroid treatment, giant and moderate size infantile haemangiomas are challenging problems, especially in health systems with limited resources in developing countries.

Case presentation

A one-year old boy was presented to us by his parents with a moderate size haemangioma on the posterior triangle of the left side of the neck. Clinical assessment and radiological examinations were helpful in confirming the diagnosis. Surgical excision was performed successfully without major morbidity. Partial necrosis of the skin flap developed shortly after the operation but healing was complete in eight weeks. There was no residual problem on review five years after the operation.

Conclusion

Early surgical excision of a moderate size infantile haemangioma may be justified especially when there is difficulty of follow-up, which can be a common problem in developing countries. This approach will prevent growth deformation, impact on nearby vital organs and psychological problems.

Introduction

Infantile haemangioma (IH) is the commonest benign tumour of infancy [1]. Knowledge about the differential diagnosis can enable clinicians to detect haemangiomas that may lead to complications that will necessitate a multidisciplinary approach [2]. Although the majority of patients are treated conservatively, there is a need for surgical resection in certain cases depending on the size and site of the lesion and parental preference for a specific intervention. However, patients do respond very well to the wait and see policy and to steroid therapy.

Case presentation

A one-year-old boy was presented by his parents to the outpatient clinic at Alburaihy Hospital in Taiz in Yemen in October 1999. The family described a progressive enlargement of a lump on the left side of the neck of an otherwise healthy infant.

Examination confirmed a 7 × 10 cm vascular tumour at the posterior triangle of the neck on the left side(see figure 1, 2). Full blood count, biochemistry, chest and neck X-rays were reported as normal apart from the soft tissue mass on the left side of the neck.
Figure 1

Anterolateral preoperative view.

Figure 2

Posterolateral preoperative view.

Ultrasound examination confirmed the cystic nature of the mass and a provisional diagnosis of infantile haemangioma was made. The wait and see policy, steroid and surgical options were explained to the parents and they chose surgery.

Successful resection of the haemangioma was performed through an elliptical incision parallel to the posterior edge of the sternomastoid muscle.

Unfortunately, the operation was complicated by necrosis of the skin at the closure site. This was treated conservatively by wound dressings. No other morbidities were reported. During the subsequent follow-up, the wound healed completely in two months. At review after five years, the child was healthy and had no residual problems (see figure 3).
Figure 3

Five years after the operation.

Discussion

In developing countries, a lack of expertise is a key factor in many health issues including the management of complex vascular lesions of the head and neck. The approach to this lesion could be conservative or surgical, depending on certain factors including the age of the patient, and the size and site of the lesion. In order to prevent possible irreversible pressure complications, early diagnosis is important to manage vascular malformations correctly because of their distinct differences in morbidity, prognosis and treatment [3].

On the other hand, the social factors and associated problems of health settings in developing countries, including difficulties with follow up, the desire of the parents for immediate cure of the problem, and the variable success rates of the different conservative treatment modalities, may lead to a preference towards surgical excision. This may be the best option treatment for some but of course not all cases of IH.

Infantile haemangioma is a common problem. In a study of 900 patients, IH accounted for 25% of soft tissue tumors [4].

There is female predisposition especially for syndromes associated with haemangioma [5]. Most hemangiomas are easily diagnosed without any additional diagnostic tests such as magnetic resonance imaging MRI and the natural course of immature haemangiomas in infants is well known. The characteristic MRI findings include a focal, lobulated soft-tissue mass that is isointense relative to muscle on T1-weighted images and hyperintense on T2-weighted images. It has diffuse and homogenous contrast enhancement and dilated feeding and draining vessels within and around the mass [6]. Ultrasound examination US may be used during the initial assessment or in place of MRI if it is unavailable. High vessel density and high peak arterial Doppler shift can be used to distinguish haemangiomas from other soft-tissue masses with high sensitivity and specificity [7].

Since most of these lesions remain asymptomatic and resolve spontaneously, conservative management is generally the rule [8, 9]. Nevertheless, the treatment options include surgical and non-surgical methods. Systemic steroid therapy may be indicated in IH and the reported success is documented [10, 11]. Corticosteroid treatment, although recognized worldwide as a treatment of problematic haemangiomas cannot always control the growth of alarming haemangiomas [12]. In these cases surgical excision may be indicated.

Furthermore, for patients with severe problems, giant growth, and local complications surgical treatment can be a wise decision [13]. Early surgery can be proposed in order to avoid definitive deformation or growth impairment of adjacent structures. It should be performed before school age and before the occurrence of psychological difficulties [14].

The surgeon should be well prepared for intra-operative and post-operative complications of excision of large neck haemangiomas. Iatrogenic injury to adjacent vital structures, such as major vessels; nerves, airway, and gastrointestinal tract (especially with deeper lesions), are the most important morbidities. Skin and soft tissue complications are less risky and can be managed successfully in the majority of cases. Skin necrosis was reported in our patient. This was anticipated because of the size of the lesion and the adherence of the skin to the hemangioma. It was managed by frequent dressings and outpatient assessment. No plastic procedure was performed because complete healing was ensured two months after the operation.

Conclusion

Early surgical resection of infantile haemangiomas can be a successful management option, especially for giant lesions. This approach will prevent growth deformation, impact on nearby vital organs and psychological problems.

Consent

Written informed consent was obtained from the patient's parents for publication of this case report and accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.

Abbreviations

IH: 

Infantile haemangioma

US: 

Ultrasound examination

MRI: 

Magnetic resonance imaging

Declarations

Acknowledgements

We thank Jackie Nicholls (RGN, ASP) who revised the language.

There was no funding for this study.

Authors’ Affiliations

(1)
General surgery department, Princess Royal University Hospital
(2)
General surgery department, Alburaihy hospital

References

  1. Vlahovic A, Simic R, Kravljanac D: Circular excision and purse-string suture technique in the management of facial hemangiomas. Int J Pediatr Otorhinolaryngol. 2007, 71: 1311-5. 10.1016/j.ijporl.2007.04.004.View ArticlePubMedGoogle Scholar
  2. Dompmartin A, Boon LM, Labbe D: Infantile hemangiomas: differential diagnosis and associated anomalies. Ann Chir Plast Esthet. 2006, 51: 300-9. 10.1016/j.anplas.2006.07.003.View ArticlePubMedGoogle Scholar
  3. Garzon MC, Huang JT, Enjolras O, Frieden IJ: Vascular malformations: Part I. J Am Acad Dermatol. 2007, 56: 353-70. 10.1016/j.jaad.2006.05.069.View ArticlePubMedGoogle Scholar
  4. Coffin CM, Dehner LP, Annu Pathol: Vascular tumors in children and adolescents: a clinicopathologic study of 228 tumors in 222 patients. 1993, 28 (Pt 1): 97-120.Google Scholar
  5. Gorlin RJ, Kantaputra P, Aughton DJ, Mulliken JB: Marked female predilection in some syndromes associated with facial hemangiomas. Am J Med Genet. 1994, 52: 130-5. 10.1002/ajmg.1320520203.View ArticlePubMedGoogle Scholar
  6. Burrows PE, Laor T, Paltiel H, Robertson RL: Diagnostic imaging in the evaluation of vascular birthmarks. Dermatol Clin. 1998, 16: 455-88. 10.1016/S0733-8635(05)70246-1.View ArticlePubMedGoogle Scholar
  7. Dubois J, Patriquin HB, Garel L, Powell J, Filiatrault D, David M, Grignon A: Soft-tissue hemangiomas in infants and children: diagnosis using Doppler sonography. AJR Am J Roentgenol. 1998, 171: 247-52.View ArticlePubMedGoogle Scholar
  8. Ceisler EJ, Santos L, Blei F: Periocular hemangiomas: what every physician should know. Pediatr Dermatol. 2004, 21: 1-9. 10.1111/j.0736-8046.2004.21101.x.View ArticlePubMedGoogle Scholar
  9. Picard A, Soupre V, Diner PA, Buis J, Goga D, Vazquez MP: Early surgery of immature hemangiomas with the aid of an ultrasonic scalpel. Apropos of 81 cases Rev Stomatol Chir Maxillofac. 2002, 103 (1): 10-21.PubMedGoogle Scholar
  10. Dourmishev LA, Dourmishev AL: Craniofacial cavernous hemangioma: succesful treatment with methylprednisolone. Acta Dermatovenerol Alp Panonica Adriat. 2005, 14: 49-52.Google Scholar
  11. Uysal KM, Olgun N, Erbay A, Sarialioglu F: High-dose oral methylprednisolone therapy in childhood haemangiomas. Pediatr Hematol Oncol. 2001, 18: 335-41. 10.1080/088800101300312609.View ArticlePubMedGoogle Scholar
  12. Enjolras O, Brevière GM, Roger G, Tovi M, Pellegrino B, Varotti E, Soupre V, Picard A, Leverger G: Vincristine treatment for function- and life-threatening infantile hemangioma. Arch Pediatr. 2004, 11: 99-107. 10.1016/j.arcped.2003.10.014.View ArticlePubMedGoogle Scholar
  13. Schmelzle R: Vascular and neural malformations. Mund Kiefer Gesichtschir. 2000, 4 (Suppl 1): S76-83.View ArticlePubMedGoogle Scholar
  14. Degardin-Capon N, Martinot-Duquennoy V, Patenotre P, Breviere GM, Piette F, Pellerin P: Early surgical treatment of cutaneous haemangiomas. Ann Chir Plast Esthet. 2006, 51 (4–5): 321-329. 10.1016/j.anplas.2006.07.019.View ArticlePubMedGoogle Scholar

Copyright

© Hussain et al; licensee BioMed Central Ltd. 2008

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.